NSAIDs and blood pressure

Home > News & Events > Newsletters

	Newsletters
	Media Releases
	Conferences
	Photo Library

NSAIDs and blood pressure
Short-term use of NSAIDs has no significant effect on blood pressure in healthy people, say specialists at London's National Heart and Lung Institute (J Hypertens 2006;24:1457-69).

Their analysis of published evidence found that healthy people with normal blood pressure who take an NSAID for up to 2 weeks do not experience a significant increase in blood pressure. People who have hypertension are more likely to have an increase in blood pressure but its magnitude is unpredictable and depends on age, blood pressure, antihypertensive treatment (possibly least impact with ACE inhibitors and some calcium channel blockers) and the type of NSAID. The size of any effect is similar with NSAIDs and paracetamol and slightly smaller with low-dose aspirin.

The new analysis confirms the finding of a 1993 meta-analysis that NSAIDs have markedly different effects on blood pressure (Arch Intern Med 1993;153:477-84). That review concluded that the average effects of short-term use of ibuprofen were negligible.

Contact us
For more information.